**STEELMAN:** This research represents a meaningful advancement in connectomics, leveraging AI to reduce the manual labor required for brain mapping. The 4.4% error reduction may seem small, but at scale, it translates to massive efficiency gains—157 years of human effort saved for a mouse brain. The open-source release of MoGen demonstrates a commitment to collaborative science, and the approach of using synthetic data to improve AI models is a proven strategy in other fields. The team acknowle...