Global X just gave investors more optionality with regard to the Invesco QQQ ETF (QQQ). The firm just launched the Global X NYSE 100 ETF (NYSX), designed to track the NYSE 100 Index. This would give investors a concentrated play on the 100 largest and most innovative companies listed across the New York Stock Exchange, NYSE American, NYSE Arca, Nasdaq, and CBOE BZX exchanges.
“This launch marks a significant milestone in Global X’s evolution as an ETF innovator,” said Ryan O’Connor, CEO of Global X. “Collaborating with NYSE to launch this fund reflects our commitment to building products that don’t just follow the market, they redefine how investors access it. NYSX is exactly the kind of intentional, forward-thinking solution we believe investors have been looking for.”
NYSX vs. QQQ: Under the Hoods
QQQ has been the default level of exposure for capturing tech-enabled growth. However, NYSX could prove a worthy challenger. NYSX has an expense ratio of nine basis points less than QQQ (0.18 for QQQ and 0.09 for NYSX). Additionally, NYSX offers a degree of variation when popping the hoods of both funds.
A fundamental difference, juxtaposing the two, is the listing requirement. QQQ is isolated to constituents listed on the Nasdaq exchange, thereby adding more concentrated exposure. Conversely, NYSX can scour the aforementioned exchanges to achieve its own tech innovation exposure.
In previous years, the NYSE was the domain of large, high-moat giants. Meanwhile, the Nasdaq leaned toward early-stage tech companies. As technological advancements have permeated all sectors, NYSE is now the residence for tech-focused growth companies — from enterprise software leaders to fintech pioneers.
With megacap tech names finding themselves in discussions that involve words like “overvaluation,” diversification is key. That said, the NYSE 100 Index isn’t just a pure-play software and hardware index relegated to the tech sector. It includes tech-enabled leaders across various sectors such as healthcare, financials, and consumer discretionary. The byproduct is a portfolio designed to track growth in the digital age without the volatility inherent in tech-sector only exposure.
“The way technology gets defined in most indexes hasn’t kept pace with how innovation actually works,” said Pedro Palandrani, head of product research & development at Global X. “NYSX was purpose-built to change that, seeking to deliver investors deliberate exposure to real innovation, across sectors and exchanges, in a way that traditional benchmarks generally do not today.”
When comparing the rosters, the top 10 holdings appear identical, but their weightings and sector leanings will vary. Analogous to sports, it would be akin to two different managers with access to the same players, but with the autonomy to perform load management and adjust the playing minutes.
Top 20 Holdings Comparison (NYSX as of 3/26/26 and QQQ as of 3/24/26)
However, the next 10 holdings (11–20) start to show the divergences between the two. Running with the sports analogy, this would be similar to where the supporting cast that complements the All-Stars is the key differentiator in constructing a championship team.
| Rank | NYSX | Weight | QQQ | Weight |
| 11 | ASML Holding NV | 2.66% | Costco Wholesale Corp | 2.40% |
| 12 | Visa Inc-Class A Shares | 2.51% | Micron Technology Inc | 2.39% |
| 13 | Micron Technology Inc | 2.11% | Netflix Inc | 2.16% |
| 14 | Mastercard Inc – A | 2.02% | Advanced Micro Devices Inc | 1.99% |
| 15 | Netflix Inc | 1.91% | Palantir Technologies Inc | 1.97% |
| 16 | Advanced Micro Devices | 1.77% | Cisco Systems Inc | 1.79% |
| 17 | Palantir Technologies Inc-A | 1.68% | Applied Materials Inc | 1.63% |
| 18 | Cisco Systems Inc | 1.59% | Lam Research Corp | 1.62% |
| 19 | Alibaba Group Holding-SP ADR | 1.52% | Intel Corp | 1.31% |
| 20 | Applied Materials Inc | 1.45% | T-Mobile US Inc | 1.29% |
High-Quality Diversifier
Again, by focusing on the NYSE 100, Global X gives investors a tech-focused growth alternative sans the concentration risk that typically comes with being anchored down to a single exchange. As Global X noted in a press release, NYSX is ideal for investors seeking exposure to best-in-class innovators who meet the rigorous listing standards inherent in the NYSE and others.
For investors seeking to mitigate Nasdaq-specific concentration risk while achieving exposure to large-cap growth, NYSX is a compelling, high-quality sector diversifier.
“A technology focused ETF with exposure across multiple sectors gives investors a way to participate in a more complete view of the innovation driving the American economy,” said Lynn Martin, president of NYSE Group. “We’re pleased to work with Global X as it introduces a new, inclusive ETF that aims to truly track the performance that investors seek from actively traded and growth-focused tech companies.”
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